journey frontiers recenzja

Frontiers by Journey

Album Reviews 1983 Albums , 2013 Reviews , Album Reviews by Ric Albano , American Artists , California Artists , Journey 0

buy Frontiers

Musically on Frontiers , the band made a concerted effort to move away from (albeit very slightly) the consistent, commercial formula which they had forged over their recent previous albums. However, they may have chosen the wrong direction in which to deviate from the pop/rock sound, primarily by making this album more synth-heavy than anything previously. Although he had emerged as the band’s chief songwriter, Jonathan Cain has a bit over the overall vibe with his keyboard work, and it caused some missed opportunities with the album’s sound. Further, bassist Ross Valory abandoned his unique, fret-less buzz which he had mastered on Escape for a more traditional rhythm sound. This would be Valory’s final album with Journey for over a decade, as he and drummer Steve Smith were replaced in 1985, only to return for the Journey mid-nineties reunion a decade later.

Left out of the final cut of the album was the future hit “Only the Young”, which eventually appeared on the soundtrack to the 1985 film Vision Quest and reached the Top Ten. This song is dominated by a consistent, almost-acoustic riff, a strong rhythm, guitar textures and vocal melodies along with with a striking message – “only the young can say they’re free to fly away…” – which shows just how talented Journey can be when all the elements are maximized.

Sequentially, the album is quite out of balance, with all five songs from the original first side released as singles (and all becoming radio hits), while none of the five from side two received any significant radio play. “Separate Ways (Worlds Apart)” starts things off, with Cain’s keyboard riff biting and eerie, like if Pink Floyd went pop. This couples with Schon’s rifle-sharp guitar track during the song proper to make for a very powerful and driving rhythm. Written in early 1982, “Separate Ways” is the oldest composition on the album and it peaked at #8 on the charts, making it the highest charting hit on the album. The calm “Send Her My Love” follows as the album’s first ballad. The song is built on a bluesy piano riff which is accented brilliantly by subtle guitar licks and some swelling sonic textures from all directions. Perry’s melody is left to carry the tune pretty much throughout until it breaks into more intense outro led by Schon’s lead guitar.

The middle of side one contains a couple of strong rockers. “Chain Reaction” is kind of boilerplate on the surface but is executed brilliantly by the band, giving it a unique edge. The rich vocal harmonies above this most guitar and riff heavy of tracks, gives it an air that it could have been an eighties hair metal classic if performed by the right group. “After the Fall” is a true pop gem, very rich and melodic throughout. This song is led by Perry’s vocals, which are at their absolute peak here, and brought out perfectly by the rest of band playing a reserved, supporting role. In between the vocals, the guitar and keyboard harmonized riff acts as a perfect counter-melody and “After the Fall” is one of the few tracks on the album where Valory’s bass is clear and up-front. The real highlight of the song is the commencement of third verse, which demonstrates how pure performance can overtake lack of fresh lyrics.

The first side concludes with “Faithfully”, the all-time, ultimate “power ballad”. While very slow and deliberate, the song packs a mighty punch, especially as it builds towards a perfect climax at the end. Written solely by Cain, the “rolling” piano riff was inspired by the sound of wheels constantly present while traveling on tour, with the simple lyrical message of keeping a relationship together while touring in a rock band. While the song is totally Cain’s in composition, the performance is carried mainly by Perry and Schon and this hit song reached #12 on the charts.

The second side is much less even than the first. “Edge of the Blade” sounds like it falls about ten minutes short of the hour, in both composition and production. While there are some good individual elements to this song, as a whole it doesn’t work at the quality we expect from Journey. “Troubled Child” is a bit better, although built on rather cheesy synths (which otherwise might have been some good riffing). The song has a dark and soulful core and is a bit off-beat, which makes it interesting. Drummer Smith added a strong enough drum pattern to take a songwriting credit for “Back Talk”, a song which takes an almost-Van-Halen-like approach musically and sounds like it would fit in perfectly with some type of theatre production lyrically. The title song “Frontiers” is the weakest song on the album and may be as close to filler as you’ll hear on a Journey album.

“Make a move across the Rubicon, futures knockin’ at your door Take your time and choose the road you want, opportunity is yours…”

The closer “Rubicon” is the only true gem on the second side. Musically choppy and moody but lyrically inspired (this could have been a theme for a Rocky film), the song possesses a great theme and concept which, even while very synth heavy, makes it feel like a true rock anthem which could have existed in many eras.

At the top of their commercial game after the success of Frontiers , Journey made a common mistake – they took too much time off and got lost from the musical scene. Perry did put out a very successful solo album called Street Talk in 1984, and the band released a songs for Soundtrack albums (including “Only the Young”) during that time period. But by the time the band returned for their next studio album, Raised on Radio in 1986 (without Valory and Smith), it was clear that the golden age of the band was over.

Part of Classic Rock Review’s celebration of 1983 albums.

Related Posts

Album Reviews

Diamonds In the Coal by The Badlees

Street Survivors by Lynyrd Skynyrd

Human Touch & Lucky Town by Bruce Springsteen

Leave a reply cancel reply.

Your email address will not be published. Required fields are marked *

2 Loud 2 Old Music

“My First Time” with Journey’s ‘Frontiers’

Love It or Hate It, Journey went down a whole new path with the release of ‘Frontiers’. After the incredible success of the album, ‘Escape’, the ballad became King for Journey. Some feel it was the start of the downfall, others think it is the pinnacle of their success. I think it is a little of both.

With the success of ‘Escape’, Journey was catapulted into the stratosphere of popularity. They were one of the biggest bands in the world.  Steve Perry had the most recognizable voices on the radio and probably one of the absolute best voices on the radio at the time…if not ever.  The man could sing.  But for some reason I still hadn’t bought a Journey album.  When I heard their second single of their latest album, ‘Frontiers’, I finally bought my first Journey album.  The single was for “Faithfully”.

There is so much to love about this album and there is so much to pick on the band for about this album.  Let’s start with the picking on piece first as it is the most fun.  Oh, where to begin…

Let’s start with the album cover…I picture of a futuristic, robotic looking head or maybe a futuristic, human head.  Not sure I get it, but I know it has to do with the name of the album, ‘Frontiers’ as I think the band was saying they were reaching into a new frontier. The amazing artwork from the previous albums was no more.  The whole continuity between all the other album covers was gone…and is sadly missed.

There was a web page I found with an interview of Jim Welch by Scott Sullivan of the Journey www page .  Jim Welch worked on the album designs for Journey.  Here is what he said when he was asked about the design and concept of the Journey album covers.

Think of the Star Wars stories. There is a constant theme throughout. I always felt that Journey’s music was transcendent. It took you to a higher level, if you wanted it to. It was also connected to the elements. The band had a style and grace that weaves through every record. We used the Scarab, the Mobeus strip, circular forms, wings and nature. Frontiers was a subtle shift. Mouse and Kelley were not involved with that cover. My vision for Frontiers was based on “tunnels” and the relativity of time and motion. Light stays the same, but time bends. It was Einstein theories for artist interpretation. The alien in Frontiers wasn’t really an alien at all, he was a connection to a higher level of listening to Journey. We called him “Elmo”. For the Frontiers tour, Jonathan Cain wrote, and the band used “Elmo’s theme” to open the show.

But when you flip over the album cover, you get them sky diving in those silly sky diving outfits.  Awful.

Oh, let’s not forget the horrible band member shots taken with these same outfits that is on the album sleeve…embarrassing in my book.  Their creative director should be fired.

Really, really gawd awful!!

What next…the video game!!  The band actually had a video game based on the album where you had to reunite the band with their instruments.  Ohh…sounds like fun…no, not really.  Check out this Youtube video of the game.  I think I played it once out in the arcade.

Okay, that is enough negative for now.  I will pick on a couple other things later.  So let’s talk about what the band did get right.  That is easy.  It is the music.  And the music is all that really matters anyway.

The album only reached #2 on the Billboard charts which is really surprising to me. They had four Top 40 singles off the album yet they were unable to hit #1.  They had a 5th single, but it was only released in Japan in case you were wondering.

• “Separate Ways (Worlds Apart)”
• “Send Her My Love”
• “Chain Reaction”
• “After the Fall”
• “Faithfully”

The first song “Separate Ways (World’s Apart)” was also the first single.  I figured they would start off with a ballad after the success of “Open Arms” , but they went with an upbeat rocker.  The song was great and reached #8 on the Hot 100.  The opening keyboard is instantly recognizable and the overall tempo made for a great opening track.  The problem with the song wasn’t actually the song, but it was that horrendous music video.  The concept was outright horrible. They band pretended to play imaginary instruments and looked so stupid doing it.  Thanks goodness they didn’t repeat that with their other videos.  It has to be one of the worst videos ever made.

The second track is one of my personal favorites, “Send Her My Love” .  This was their fourth single and the first of many ballads on the album.  The song only went as high as #23 on the charts as I am sure radio was starting to tire of the ballads at this point.  I like mainly because Steve Perry sounds incredible as usual.  After Journey left, one of the many singers they had was Jeff Scott Soto.  He had done a cover of this song and was so amazing, I am sure it was what helped him get the job.  Sadly, they never put out an album with Soto as singer.  He only sang on the tour as they had to replace Steve Augeri.

“Chain Reaction” was the third track and another rocker. This is the first of many with Neal Schon assisting on the writing.  For me, this was one of the better songs on the album and could have easily been a single.  It did, however, do well on rock radio stations.

The third single and fourth track was “After the Fall” .  The song did okay on the charts reaching #23 on the charts, but for me it really lacked any heart.  It was too bland for my liking and I find myself skipping it when I listen to the album. So I will skip writing much about it.

The song that finally sold me on buying a Journey album was “Faithfully” .  The sad ballad about life on the road and away from your loved ones had such a beautiful sentiment mixed with those amazing vocals what was not to love about this song.  Jonathan Cain was the sole writer of this masterpiece.  The song only hit #12 on the charts and I have no idea how this didn’t got to #1.  The video for the song matched perfectly the songs theme. It was one of those videos where the video actually enhanced the song. It was a perfect match.

• “Edge of the Blade”
• “Troubled Child”
• “Back Talk”
• “Frontiers”
• “Rubicon”

The flip side of the album didn’t have any singles which doesn’t mean this side isn’t worth listening to it.  At times, I like it better than the first.  If you want great deep cuts off an album, this is the side to give a listen.   “Edge of the Blade” kicks it off in style with another rocker.  The guitar sound to start of is unique and then kicks in with some pounding drums.  It is this type of song that I think Journey really excels.  Neal Schon is so great at what he does and it shines on this one throughout.  I also like that he has his hands in most of the songwriting on this side.  He was lacking on the front.

Another personal favorite of mine is “Troubled Child” .  Jonathan Cain’s starts off beautifully with another great keyboard opening.  The song is another ballad but more on the power ballad side.  The chorus is a little heavier and Steve Perry hangs on to a note that seems to last forever.  It is stunning.

“Back Talk” brings a tribal drum beat to the opening and Steve gives a more edgy vocal performance.  The follow suit with rocker, ballad, and another rocker formula again here.  There is also more great guitar work by Schon. The funny thing is I never liked this song when I listened to it back in the 80’s as it was too different.  Now, that is exactly why I like it.  It is funny how tastes change over time.

An interesting note about “Troubled Child” and “Back Talk” , they were last minute replacements on the album.  The two songs that were scrapped, but later released were “Only the Young” off the Vision Quest Soundtrack and “Ask the Lonely” off the Two of A Kind Soundtrack.  They were later added to the album for the 2006 Remastering of the album.  Some would say those two songs were better than what they used, but that is purely a matter of opinion.

The title track, “Frontiers” is not one of my favorites.  I don’t hate it, but I don’t love it either.  It does have a catchy chorus and Steve kills it on that part, but the rest leaves me wanting more.  It seems a little disconnected at times.  I do like how the song ends with Steve’s vocals.

The final song is another one I think is great, “Rubicon” .  Neal Schon kicks it off with a nice guitar riff.  It is a simple song, not much to it, but Steve Perry proves one more time why he was the king.  When you are done with this side, you realize that Journey is definitely more than their singles.  It was because of this side that I would venture back and explore all of their earlier releases to see what hidden gems I could fine…and there are many.

If you want the lyrics, the album sleeve kindling gives you those even though I found them a little hard to read due to the yellow color of the font and the almost pinkish background.  See what you think (I know you can’t read it as it is too small in the picture, but you hopefully see what I mean).

And there we have another “My First Time” experience.  I don’t think there are too many shortcomings with the album and it is one I still listen to even after 31 years of having it.  And I am sure I will continue to enjoy it for years to come.  I hope you enjoyed my ramblings.

Share this:

20 thoughts on “ “My First Time” with Journey’s ‘Frontiers’ ”

The video game?! What the actual f…?

I’m going to have to go back to this one. I could never really get into it. The first track is so amazing that I always kinda switch off after it! The albums either side suited me better.

Like Liked by 2 people

It is always worth a revisit every now and again. And yes, there was a video game.

Like Liked by 1 person

I’m not familiar with anything by Journey, but I always stop flicking through the LPs when I spot one of their covers. This one is pretty excellent, too… makes me think of Darth Vader!

I like the bug covers myself. They got away from it for a few albums, but I definitely prefer the bugs.

I have never heard a note of this album – I put this down to living in Wales, we were that backwards we didn’t have the 1980’s just two lots of the 70s and then straight on to grunge.

You missing not knowing a few of these songs. Not my favorite journey album, but holds a little place in my heart as my first journey album.

The video of Separate Ways ruined it for me! Billy Squier lost his career over a video but at least Journey weren’t jumping around on a bed in this video. Just getting high and pretending to play your instruments is just wrong…. Don’t know which is worse!

I think it was just as bad as Squier’s overall. Billy’s video didn’t make him manly (not that there is anything wrong with that) and that was the Kiss of death in those days.

I checked — I’m missing this!

Really! Wow. I can’t believe it. I thought you had everything! 😀

I’m still completing my Journey collection! I knew about the video game thing but never seen it before! Lol

I ❤ Journey in 2017! Lol you’re right about the “Separate Ways” video. What is that female wearing?? 😂 Black panty hose with white pumps! OK! Maybe they were just trying to be funny.

I think maybe they were high or drink or both. 😂

Lol probably! I prefer Steve Perry over Arnel Pineda. He sounds a lot like Steve Perry though. They’re coming to El Paso in July. I get to write a story about them for one of my freelance gigs. Still no interview though! Lol.

Cool on the story and too bad on the interview. They are having some personnel issues right now between Neal and Jonathan. They aren’t getting along well now. Arnel is a cool story though. Kudos to him.

I’ve literally just got into Journey in the last week! You know what? I love the Seperate Ways video – the humour is lost on everybody. The woman’s dress typifies England 80s – watch any video of that era. And I love the syncopation of the band playing imaginary instruments – notice how they appear after a few seconds. And I just love the aggression and swagger of the band members. Finally, as a healthy sexual heterosexual male, I find Steve Perry getting me on my knees – the ‘In vain’ x3 segment is just fucking killer. His voice here is just out of the fucking universe.

“Only The Young” and “Ask the Lonely” are probably my two favourite songs from this album so it is interesting to hear they were only added later.

A video game? Wow ….

Love Journey’s classic stuff. Got to say not a big fan of their new stuff since they got their new singer. Much prefer Foreigner’s new singer Kelly Hansen.

Agreed. Journey has not been able to recapture any magic after Steve left. It is sad now to see Neal Schon and Jonathan Cain battling each other online. I think Cain will no longer be in the bad soon (if not already).

Frontiers is by FAR the better album. Even more than Escape! It was different, fresh, killer, provocative, with way more hard rock almost metal (Troubled Child, Edge of the Blade) than anything since! They were trying to capture the hard rock fans who, in public, thought Journey too soft but in private, were die hard fans. I LOVE the Separate Ways video. It looked like the 80s and was when MTV was just starting out. MTV OWES Journey a HUGE debt!

Thanks for commenting. It is a great one and I do love Troubled Child. Yes, these guys were all over MTV and I think Faithfully was played every hour it seemed like. Separate Ways was such an awful video but a great song.

Leave a comment Cancel reply

• Already have a WordPress.com account? Log in now.
• Subscribe Subscribed
• Copy shortlink
• Report this content
• View post in Reader
• Manage subscriptions
• Collapse this bar

• Rolling Stones 2024 Tour Openers
• Best Four-Album Run in Rock
• Rik Emmett on the Mainstream
• Simmons Post-Kiss Solo Show
• Rock Hall 2024 Roundtable

How Journey’s ‘Frontiers’ Could Have Been Their Best ’80s Album

It's hard to argue with the success surrounding Journey 's eighth studio album. Released in February 1983, the six-times-platinum Frontiers reached No. 2 in the U.S., spawned four Billboard Top 40 singles and became Journey's highest-charting U.K. release. But it still could have been a much better album.

Side One is overstuffed with radio-made favorites, including the No. 8 smash "Separate Ways (Worlds Apart)," the No. 12 ballad "Faithfully" and a pair songs that made it to No. 23: "After the Fall" and "Send Her My Love." The record falls off considerably, however, on its second side, and that ended up keeping Frontiers from passing 1981's Escape as Journey's best '80s album.

So, what happened? Had Journey, coming off their biggest year ever, simply run out of gas creatively? Were the seeds of future issues that surfaced during the Raised on Radio era already being sown?

Actually, the answer as to why Frontiers loses so much momentum so quickly is far more rudimentary: A record-label guy screwed everything up.

The song lineup was already confirmed, and Frontiers was set to be pressed, when an A&R rep decided that Journey should pull two songs for use on contemporary soundtracks. "Only the Young" and "Ask the Lonely" were replaced by "Back Talk" and "Troubled Child."

Side Two suddenly began to take shape as something distinct from what came before – both on Frontiers and for the band itself. It was edgier, a bit more experimental. "No one can say that songs like 'Back Talk' or 'Edge of the Blade' are reminiscent of things that appeared on Escape ," Steve Perry told Hit Parader in 1983. "We've got to keep challenging ourselves to keep things interesting."

The problem wasn't their gumption; it was the relative quality of the replacement songs: "Troubled Child" is the album's worst moment. Meanwhile, "Only the Young" emerged as a bona-fide hit after finally being released in 1985. Now forever linked to a dying boy's final wish, the song would have become the centerpiece of the concluding half of Frontiers .

Instead, "Only the Young" languished for years, showing up as a cover on Scandal's 1984 album Warrior before eventually finding a home on the Vision Quest soundtrack in 1985. All of a sudden, Journey had the No. 9 hit that Frontiers always deserved, and only then did the song's remarkable backstory become more widely known.

Listen to Journey's 'Only Solutions'

The first person outside of Journey's inner circle to hear the song was Kenny Sykaluk, a 16-year-old Ohio native battling a terminal case of cystic fibrosis. His mother had written Journey in the hopes they could visit Sykaluk, and they made an emotional trip to his bedside in Cleveland.

Neal Schon said Sykaluk's attitude in the face of such adversity put everything in perspective for the band, which was already experiencing no small amount of friction. "As soon as I stepped out of that hospital room, I lost it," Perry said in the liner notes to the Time3 box set. "Nurses had to take me to a room by myself."

They gave Sykaluk a Walkman cassette player with a copy of "Only the Young" inside, along with other special items. He died the very next day.

"Here's this little kid, struggling for every breath. We were doing everything in our power not to break down and bawl in front of him," a tearful Jonathan Cain said during the band's episode of VH1's Behind the Music . "That song will always be his song."

Journey ended up opening every concert with "Only the Young" during the Raised on Radio tour, their last with Perry.

Frontiers also could have featured "Only Solutions," which instead was lost to the Tron  movie. This underrated 1982 song grew out of a studio jam between Cain and Schon, and finds Journey loosening up during a period of intense scrutiny and expectation. ("If it sounds like something we made up on the spot in the studio," Schon said in Time3 , "that's because it is.") "Only Solutions" was instead added at the last moment to the Walt Disney movie's closing titles; in fact, it was so late that the song couldn't be included on Tron 's official soundtrack.

Another prospective track, Cain's "Allies," appeared on Heart 's 1983 album Passionworks . "Ask the Lonely," meanwhile, was a patented Perry-Cain mid-tempo number – and maybe that led to the tune's overlooked status. Perry seemingly dismissed it as "just a love song," while Cain marveled at the former Journey singer's ability to "write love songs in his sleep." It certainly would have helped ground Side Two. In the end, however, "Ask the Lonely" got tucked away on the soundtrack to Two of a Kind , a 1983 flop reunion film starring Grease vets  John Travolta and Olivia Newton-John.

A 2006 expanded reissue of Frontiers attempted to set things right and included a quartet of songs from the same sessions that would have greatly improved the final product: "Only the Young," "Ask the Lonely," "Only Solutions" and "Liberty," a layered, patriotic tune that was also left on the cutting-room floor. By then, Perry was long gone .

The Best Song From Every Journey Album

See Neal Schon Among Rock’s Forgotten Supergroups

More From Ultimate Classic Rock

• I Love Classic Rock on Facebook

Artists - A-H

• Ace Frehley
• Alex Lifeson

Artists - I-P

• Iron Maiden
• J. Geils Band
• Jaco Pastorius
• James Brown

Artists - Q-Z

• Randy Meisner
• Randy Rhoads

• Unheard 1966 Beatles Cassette Tapes Set...
• David Lee Roth Disses Sammy Hagar...
• Sammy Hagar Explains His Alien Theory

• Dave Mustaine Explains Why He Thinks...
• Ozzy Osbourne Explains Why He Rejected...
• Bruce Dickinson Shows You How Not...

• Joe Bonamassa Unveils Ode to Peter...
• We Explore The Genius Behind Bill...
• 25 Greatest Chicago Blues Songs

Album Review: “Frontiers” By Journey

Frontiers album cover - ForeverStevePerry / Youtube

Frontiers, Journey’s eighth studio album, succeded the acclaim of its predecessor  Escape with a close commercial performance, albeit sporting a stark difference in execution.  Frontiers  veered away from the band’s pop-oriented arena rock sound and instead went for synth-heavy instrumentation that was both unorthodox yet productive for the Journey. The album also saw the exit of bassist Ross Valory and drummer Steve Smith, who returned in the next decade for a reunion.

Opening the album is  “Separate Ways (Worlds Apart)” , a synth riff courtesy of Jonathan Cain driving the song along with Neil Schon’s piercing guitar playing. Following it is the laidback ballad  “Send Her My Love”,  carrying a blues piano progression and is accentuated by Steve Perry doing the main melody before the guitar breaks off into a lead fiasco.  “Chain Reaction”  is carried by nonstop riffing that teeters on the verge of hair metal, while  “After The Fall”  takes hints of pop back into the mix with Perry taking center stage with his vocals. Ending the first side is the universally-acclaimed power ballad,  “Faithfully”,  carries the theme of keeping a relationship while being in a rock band, with the nostalgic piano progression and soaring vocals adorning its run.

The second side starts with  “Edge of The Blade”,  which is rather weak compared to the previous tracks.  “Troubled Child”  soon follows, with synths painting a brooding atmosphere and enhanced by an offbeat rhythm.  “Back Talk”  is edgy in a hard-rock kind of way, while the title track ironically doesn’t do much for the album except as a filler. Closing the entire record is  “Rubicon”,  a versatile rocker that could have done better if it stuck to the theme of the album.

Frontiers  was probably the band’s best effort before they sunk to mediocrity due to complacency.

Beach Boys Released 6 Bad Songs On Our Book

10 Facts That Makes David Bowie So Cool

Fans Didn’t Know These 4 Fleetwood Mac Songs Was…

Geddy Lee’s Ultimate Regret About Jimi Hendrix

10 Famous Musicians Who Hated Being In A Band

Eddie Van Halen Adored Only One Song In Peter…

Lars Ulrich’s Childhood Home Goes On Sale At $6.85m

• Terms Of Use
• Privacy Policy

• Pandemonium

JOURNEY - Frontiers 80%

Čas a pohyb v něm jsou relativní, světlo zůstává věčné, připravte se, přesun na počátek roku 1983 začíná. Vzpomínky na etapu nahodilých lásek k dívkám v excentrických účesech, s výraznými šminkami a oděvech se vzorem leopardí kůže zde naplno ožívají. Fantazie maká na plné obrátky. Gargantuovský zvuk kláves Jonathana Caina vás brzy upozorní, že jste na místě určení správně. Hned v úvodní, aerobně napumpované hymně „Separate Ways (Worlds Apart)“ máte pocit jízdy po strmých ulicích nočního San Francisca. V odlesku světel aut a neonů vážně čekáte, že vám co chvíli přes kapotu přeletí týpek v naducané bundičce, následován Nickem Noltem a mladým Eddiem Murphym. I o něčem podobném může být album „Frontiers“ od kalifornské kapely JOURNEY , velikánů americké AOR.

V jejich případě šlo většinou o rock, ale dokonale kultivovaný, dospělácký a uzpůsobený parametrům široké veřejnosti. Sedmé album „Escape“ z roku 1981 sklidilo desetinásobnou platinu a stanulo na vrcholu prodejních charts. O to však mělo následující „Frontiers“ těžší roli, neb zopakovat úspěch alba, jenž je řazeno mezi třicítku nejdůležitějších rockových nahrávek z USA osmdesátých let, je dost možná těžší, než podobného statusu poprvé docílit. Kaliforňanům působícím okolo skvělého kytaristy a šéfa Neala Schona a rovněž vysoce ceněného zpěváka s naléhavým a afektovaně nakřáplým tónem v hlase Steva Perryho se to však podařilo, i když napodruhé to byla platina „pouze“ šestinásobná. S Perrym u mikrofonu dostali JOURNEY na konci sedmdesátých let do své hudby esprit skutečně mainstreamové záležitosti, který zkraje následující dekády ještě zdokonalili příchodem klávesáka, skladatele a stavitele jejich nového zvuku Jonathana Caina.

Deska „Frontiers“ vznikala za hektických podmínek během podzimu 1982 ve studiích Fantasy v Berkeley a sice pod dohledem bývalého producenta QUEEN Mikea Stonea a zvukového inženýra Kevina Elsona . Mimořádně navštěvované americké turné k „Escape“ budilo nemalá očekávání i stran nových skladeb. Na svou dobu šlo nakonec o moderně znějící nahrávku, která JOURNEY etablovala mezi největší hudební instituce v zámoří první poloviny osmdesátých let. „Frontiers“, jako nejúspěšnější deska JOURNEY mimo Spojené státy, působila pestře, což zde bylo patrné v rámci kontrastů mezi dravějšími rockovými čísly jako „Chain Reaction“ a „Edge Of The Blade“  na jedné straně a o poznání poklidnějším romantickým nalazením, které zde reprezentují songy jako „Send Her My Love“ a „Faithfully“ na straně druhé.

Než Columbia album 1.února 1983 vypustila, měnilo se i složení skladeb, a tak dvě původně zamýšlené a vesměs velice chytlavé písně „Ask The Lonely“ a „Only The Young“ byly ušetřeny zveřejnění v rámci alba a odcestovaly na soundtracky tehdy aktuálních filmů. V případě první šlo o romantickou komedii „Dva podobní“ v hlavní roli s Johnem Travoltou a Olivií Newton-John , a co se týče druhé, šlo o nepříliš zajímavé sportovní drama „Hledání vidiny“ . Tyto dva chytlavé songy byly nahrazeny jinou dvojicí skladeb, konkrétně tedy drásavou „Back Talk“ , která zněla oproti zbytku materiálu o něco hruběji a stavěla na výraznějším groovu i kytarovém zvuku situovaném do popředí, a naopak také naléhavou jemnůstkou „Troubled Child“ , což byl song dokonale reprezentující onu romantickou polohu tehdejších JOURNEY. Právě posledně zmíněná píseň vlastnila potenciál srdceryvného čísla, jež je nadnášeno Cainovými závoji synťáků a v závěru zdobeno honosným Schonovým sólem.

Deska ověnčená mnoha úspěchy, které definovaly působení JOURNEY v USA první poloviny osmdesátých let, se však také stala na třináct let labutí písní dlouholetého baskytaristy Rosse Valoryho , který se do sestavy vrátil až při comebacku kapely v roce 1996. Zbytek je pak už jen historie a sice historie jedné z nejdůležitějších kapel americké scény Adult Oriented Rocku osmdesátých let. Vychutnejte si jí.

JOURNEY - Frontiers

AC/DC - Let There Be Rock QUEENSRŸCHE - Queensrÿche GREAT WHITE - Back To The Rhythm LITTLE ANGELS - Young Gods DEF LEPPARD - Def Leppard HALESTORM, BLACK VEIL BRIDES, MOTHICA - Praha, SaSaZu, 19.listopadu 2023 PRISTINE - Road Back To Ruin ZZ TOP - La Futura GUS G. - I Am The Fire LED ZEPPELIN - Led Zeppelin II KK´S PRIEST - The Sinner Rides Again QUEEN - The Works TOXIC HOLOCAUST - Primal Future: 2019 QUEENSRŸCHE - Condition Hüman AC/DC - Black Ice LUCIFER - Lucifer IV DEF LEPPARD - Pyromania PHIL CAMPBELL AND THE BASTARD SONS - EP SOTO - Praha, Nová Chmelnice, 11.dubna 2016 QUEENSRŸCHE - Promised Land

Journey In The Studio For 'Frontiers' 40th Anniversary - 2023 In Review

Pink Floyd's David Gilmour Reveals Song From First New Album In Nine Years- AC/DC Launching High Voltage Dive Bar At Stops On Power Up Tour- more

Reba McEntire to Host 59th ACM Awards- Carly Pearce Celebrates Birthday By Surprising Fans with Early Album Release Date- more

Frontiers (2023 Remaster)

February 1, 1983 10 Songs, 43 minutes ℗ 1983 Sony Music Entertainment Inc.

Music Videos

More by journey, featured on.

Apple Music ’80s

Apple Music Fitness

Apple Music Classic Rock

You Might Also Like

Steve Perry

Stevie Nicks

Bad English

Select a country or region

Africa, middle east, and india.

• Côte d’Ivoire
• Congo, The Democratic Republic Of The
• Guinea-Bissau
• Niger (English)
• Congo, Republic of
• Saudi Arabia
• Sierra Leone
• South Africa
• Tanzania, United Republic Of
• Turkmenistan
• United Arab Emirates

Asia Pacific

• Indonesia (English)
• Lao People's Democratic Republic
• Malaysia (English)
• Micronesia, Federated States of
• New Zealand
• Papua New Guinea
• Philippines
• Solomon Islands
• Bosnia and Herzegovina
• France (Français)
• Deutschland
• Luxembourg (English)
• Moldova, Republic Of
• North Macedonia
• Portugal (Português)
• Türkiye (English)
• United Kingdom

Latin America and the Caribbean

• Antigua and Barbuda
• Argentina (Español)
• Bolivia (Español)
• Virgin Islands, British
• Cayman Islands
• Chile (Español)
• Colombia (Español)
• Costa Rica (Español)
• República Dominicana
• Ecuador (Español)
• El Salvador (Español)
• Guatemala (Español)
• Honduras (Español)
• Nicaragua (Español)
• Paraguay (Español)
• St. Kitts and Nevis
• Saint Lucia
• St. Vincent and The Grenadines
• Trinidad and Tobago
• Turks and Caicos
• Uruguay (English)
• Venezuela (Español)

The United States and Canada

• Canada (English)
• Canada (Français)
• United States
• Estados Unidos (Español México)
• الولايات المتحدة
• États-Unis (Français France)
• Estados Unidos (Português Brasil)
• 美國 (繁體中文台灣)

A Journey of Postcards

• Capital Cities
• Hanseatic cities
• USA states and capitals
• The Journey so far

0 comments:

Post a comment.

Total Pageviews

Postcard of the day, temple of abu simbel | egypt.

Postcard The Abu Simbel temples are two massive rock temples at Abu Simbel, a village in Nubia, southern Egypt, near the border with Su...

Browse by keywords

Around the world in postcards, countries and territories (250).

• Abkhazia (2)
• Afghanistan (4)
• Albania (10)
• Alderney (2)
• Algeria (11)
• American Samoa (3)
• Andorra (5)
• Anguilla (2)
• Antarctic Territories (8)
• Antigua and Barbuda (4)
• Argentina (12)
• Armenia (12)
• Australia (86)
• Austria (13)
• Azerbaijan (6)
• Bahamas (11)
• Bahrain (7)
• Bangladesh (6)
• Barbados (5)
• Belarus (18)
• Belgium (21)
• Bermuda (5)
• Bolivia (3)
• Bonaire (5)
• Bosnia Herzegovina (6)
• Botswana (4)
• Brazil (27)
• British Virgin Islands (2)
• Bulgaria (13)
• Burkina Faso (6)
• Burundi (9)
• Cambodia (8)
• Cameroon (4)
• Canada (36)
• Cape Verde (5)
• Cayman Islands (3)
• Central African Republic (2)
• Christmas Island (4)
• Cocos (Keeling) Islands (1)
• Colombia (12)
• Comoros (4)
• Cook Islands (5)
• Costa Rica (9)
• Croatia (26)
• Curacao (7)
• Cyprus (26)
• Czech Republic (20)
• Denmark (15)
• Djibouti (5)
• Dominica (4)
• Dominican Republic (8)
• DR Congo (6)
• Ecuador (6)
• El Salvador (6)
• Equatorial Guinea (2)
• Eritrea (3)
• Estonia (13)
• Ethiopia (18)
• Falkland Islands (2)
• Faroe Islands (7)
• Finland (24)
• France (54)
• French Guiana (3)
• French Polynesia (4)
• Georgia (10)
• Germany (125)
• Gibraltar (4)
• Greece (33)
• Greenland (6)
• Grenada (3)
• Guadeloupe (3)
• Guatemala (10)
• Guernsey (3)
• Guinea-Bissau (1)
• Honduras (11)
• Hong Kong (11)
• Hungary (12)
• Iceland (8)
• Indonesia (30)
• Iraqi-Kurdistan (6)
• Ireland (9)
• Isle of Man (9)
• Israel (13)
• Ivory Coast (4)
• Jamaica (6)
• Kazakhstan (15)
• Kiribati (5)
• Korea South (15)
• Kyrgyzstan (3)
• La Réunion (3)
• Lebanon (52)
• Lesotho (3)
• Liberia (3)
• Liechtenstein (5)
• Lithuania (11)
• Luxembourg (3)
• Macedonia (6)
• Madagascar (8)
• Malaysia (42)
• Maldives (7)
• Marshall Islands (4)
• Martinique (2)
• Mauritania (2)
• Mauritius (8)
• Mayotte (1)
• Mexico (25)
• Micronesia (3)
• Moldova (5)
• Moldova - Transnistria (2)
• Mongolia (13)
• Montenegro (7)
• Montserrat (1)
• Morocco (14)
• Mozambique (2)
• Myanmar (9)
• Nagorno-Karabakh (1)
• Namibia (5)
• New Caledonia (6)
• New Zealand (13)
• Nicaragua (7)
• Nigeria (6)
• Norfolk Island (2)
• North Korea (7)
• Northern Cyprus (5)
• Northern Mariana Islands (2)
• Norway (23)
• Pakistan (16)
• Palestine (Gaza) (2)
• Palestine (West Bank) (2)
• Papua New Guinea (5)
• Paraguay (5)
• Philippines (22)
• Pitcairn Island (3)
• Poland (45)
• Portugal (24)
• Portugal-Azores (8)
• Portugal-Madeira (5)
• Puerto Rico (4)
• Republic of the Congo (1)
• Romania (20)
• Russia (86)
• Saint Martin (4)
• Saint-Pierre and Miquelon (2)
• San Marino (2)
• São Tomé and Principe (5)
• Saudi Arabia (9)
• Senegal (10)
• Serbia (12)
• Seychelles (5)
• Sierra Leone (1)
• Singapore (6)
• Sint Maarten (8)
• Slovakia (12)
• Slovenia (9)
• Solomon Islands (2)
• South Africa (12)
• South Sudan (1)
• SriLanka (11)
• St Barthélemy (3)
• St Helena (1)
• St Kitts and Nevis (6)
• St Lucia (6)
• St Vincent and the Grenadines (4)
• Suriname (11)
• Svalbard (2)
• Swaziland (5)
• Sweden (18)
• Switzerland (16)
• Taiwan (13)
• Tajikistan (3)
• Tanzania (45)
• Thailand (20)
• The Netherlands (25)
• Timor Leste (2)
• Tokelau (1)
• Trinidad and Tobago (8)
• Tristan da Cunha (2)
• Tunisia (16)
• Turkey (37)
• Turkmenistan (6)
• Turks and Caicos Islands (5)
• Ukraine (19)
• United Kingdom - England (35)
• United Kingdom - Northern Ireland (3)
• United Kingdom - Scotland (18)
• United Kingdom - Wales (4)
• United Nations - Geneva office (1)
• United Nations - New York office (3)
• United Nations - Vienna office (1)
• Uruguay (5)
• US Virgin Islands (3)
• USA - Hawaii (7)
• Uzbekistan (8)
• Vanuatu (7)
• Vatican City (5)
• Venezuela (6)
• Vietnam (17)
• Wallis and Futuna (1)
• Western Sahara (1)
• Zimbabwe (5)

Popular Posts

Blog Archive

• ►  February 2021 (2)
• ►  January 2021 (8)
• ►  December 2020 (2)
• ►  October 2020 (2)
• ►  September 2020 (27)
• ►  August 2020 (30)
• ►  July 2020 (31)
• ►  June 2020 (3)
• ►  April 2020 (16)
• ►  March 2020 (31)
• ►  February 2020 (31)
• ►  January 2020 (31)
• ►  December 2019 (31)
• ►  November 2019 (30)
• ►  October 2019 (31)
• ►  September 2019 (31)
• ►  August 2019 (33)
• ►  July 2019 (33)
• ►  June 2019 (32)
• ►  May 2019 (31)
• ►  April 2019 (31)
• ►  March 2019 (32)
• ►  February 2019 (29)
• ►  January 2019 (32)
• ►  December 2018 (32)
• ►  November 2018 (29)
• ►  October 2018 (31)
• ►  September 2018 (34)
• ►  August 2018 (28)
• ►  July 2018 (21)
• ►  June 2018 (25)
• ►  May 2018 (30)
• ►  April 2018 (28)
• ►  March 2018 (27)
• ►  February 2018 (25)
• ►  January 2018 (28)
• ►  December 2017 (31)
• ►  November 2017 (28)
• ►  October 2017 (30)
• ►  September 2017 (29)
• ►  August 2017 (31)
• ►  July 2017 (31)
• ►  June 2017 (28)
• ►  May 2017 (28)
• ►  April 2017 (25)
• ►  March 2017 (30)
• ►  February 2017 (28)
• ►  January 2017 (30)
• ►  December 2016 (30)
• ►  November 2016 (32)
• ►  October 2016 (36)
• ►  September 2016 (30)
• ►  August 2016 (22)
• ►  July 2016 (27)
• ►  June 2016 (17)
• ►  May 2016 (22)
• ►  April 2016 (24)
• ►  March 2016 (23)
• ►  February 2016 (19)
• ►  January 2016 (10)
• ►  December 2015 (5)
• ►  November 2015 (16)
• ►  October 2015 (22)
• ►  September 2015 (28)
• ►  August 2015 (33)
• ►  July 2015 (30)
• ►  June 2015 (32)
• ►  May 2015 (25)
• ►  April 2015 (22)
• ►  March 2015 (25)
• ►  February 2015 (19)
• ►  January 2015 (23)
• ►  December 2014 (18)
• ►  November 2014 (31)
• ►  October 2014 (27)
• ►  September 2014 (24)
• ►  August 2014 (23)
• ►  July 2014 (21)
• ►  June 2014 (20)
• ►  May 2014 (23)
• ►  April 2014 (19)
• ►  March 2014 (18)
• ►  February 2014 (21)
• ►  January 2014 (12)
• ►  December 2013 (18)
• ►  November 2013 (23)
• ►  October 2013 (32)
• ►  September 2013 (23)
• ►  August 2013 (24)
• ►  July 2013 (28)
• ►  June 2013 (16)
• ►  May 2013 (12)
• ►  April 2013 (14)
• ►  March 2013 (21)
• ►  February 2013 (18)
• ►  January 2013 (15)
• ►  December 2012 (17)
• ►  November 2012 (21)
• ►  October 2012 (19)
• ►  September 2012 (21)
• ►  August 2012 (19)
• ►  July 2012 (11)
• ►  June 2012 (10)
• ►  May 2012 (16)
• ►  April 2012 (22)
• ►  March 2012 (25)
• ►  February 2012 (23)
• ►  January 2012 (43)
• A postcard from the Cook Islands
• Sule Pagode from the Republic of the Union of Myanmar
• The Bupaya Pagoda from Myanmar
• 2011 Año Internacional de los Bosques, Mexico
• Nassau Harbour, Bahamas
• Government museum from Chennai | சென்னை, India
• A temple from Greece: the Erechtheion | Ἐρέχθειον
• Mongolian nomads
• San Francisco's Golden Gate Bridge .. from China
• Volpiano a small village in Italy
• Baseball from Cuba
• A town called Týn nad Vltavou, Czech Republic
• A map of the Russian Federation
• Fort Abraham Lincoln State Park
• City Hall San Fernando, Trinidad and Tobago
• Grand Harbour | Il-Port il-Kbir from Malta
• Feldstone tombs from Oman
• A postcard from Mongolia
• Old and new Town Hall, Chemnitz
• Litoměřice - the Garden of Bohemia
• Obudu Hills, Nigeria
• Gothic, Baroque and Oriental designs: Paoay Church...
• Great Temple of Faqra, Lebanon
• Dunes de Merzouga, Morocco | Maroc
• A postcard from Ghana
• A postcard from Sénégal
• Lissabon Tram | Lisboa Carro Electrico
• Coleccion Numismatica, Ano del Oro 2010, Venezuela
• Estancia Santa Catalina, Argentina
• Church of Sant Joan de Caselles, Andorra
• Salt Pans, Tamilnadu, India
• A poscard from Namibia: Dunes near Sesriem, Namib ...
• Saquisili Market from Ecuador
• Tortugas Gigantes from Galápagos
• A postcard from Cameroon: Transport by Motorbike
• Warren Pennsylvania, USA
• Coca Cola City: Atlanta, Georgia USA
• Ecuador by Train
• A postcard from Saudi Arabia: Ministry of Information
• Relics transportation of Euphrosyne of Polatsk, Be...
• ►  November 2011 (42)
• ►  October 2011 (55)
• ►  September 2011 (55)
• ►  August 2011 (58)
• ►  July 2011 (44)

Great Postcard Blogs

Covers and stamps

Interesting links

UC's record graduating class prepares for next chapter

Uc will recognize the biggest spring graduating class in its 205-year history.

The University of Cincinnati caters to students such as Quincy Allfree who — like the poet Walt Whitman said — contain multitudes.

The Carl H. Lindner College of Business student completed a co-op in Kentucky, earned a certificate in Spanish business and joined a mentoring fellowship all while pursuing a double major in marketing and business information systems.

He will have a large cheering section of family when he walks across the stage at Fifth Third Arena for the largest spring commencement in the 205-year history of the university based on preliminary numbers.

With four ceremonies spread across three days, UC’s spring commencement kicks off at 3 p.m. Thursday, April 25, with the doctoral hooding and master’s recognition ceremony. Doors open at 1:30 p.m. Tickets are required for all guests. The arena only allows clear plastic bags.

UC’s undergraduate commencement will consist of two ceremonies at 10 a.m. and 3 p.m. Friday, April 26, and 10 a.m. Saturday, April 27. The ceremonies will be streamed live .

UC President Neville Pinto will address a record number of graduates at spring commencement. Photo/Andrew Higley/UC Marketing + Brand

Pursuing your passions

Allfree enjoys art and drawing, but he also wanted to learn more about how to reach a bigger audience. So he double-majored in marketing and business information systems in the Lindner College of Business.

And he wanted to learn more about photography and videography, so he minored in media production in UC’s College-Conservatory of Music.

Because he likes to travel, he wanted to brush up on his language skills, so he got a certificate in business Spanish from UC’s College of Arts and Sciences.

Allfree is in UC’s Darwin T. Turner Scholars Program, where he became fast friends with his first-year roommate. The program is designed to give first-generation and underrepresented college students a community of support to help them succeed.

Allfree said being a Turner scholar made the transition to college much easier.

“I think it worked for me because I come from a small high school in Cincinnati,” he said. “I didn’t know many people at UC, so it allowed me to have a built–in community.”

Quincy Allfree, pictured center, belonged to UC Business Fellows, a professional mentorship group in UC's Carl H. Lindner College of Business. Photo/Joseph Fuqua II

Allfree joined UC Business Fellows, a mentorship program for future business leaders.

Some of his favorite experiences were trips abroad to Canada and Colombia. He traveled to Toronto in his first year at Lindner. And during spring break he went to Colombia for a study-abroad program, where he put his Spanish skills to the test.

He has a large contingent of family coming to commencement. And he’s looking forward to UC’s Afrocentric graduation celebration called Tyehimba. 

Allfree said apart from imparting new skills and knowledge, UC demonstrated the importance of kindness.

“You never know what people are going through,” he said. “Be a friend to people, even if it’s not someone you see yourself fraternizing with.”

About the spring class of 2024

UC will confer 7,521 degrees to 7,391 students. (Some students are earning multiple degrees.) Both represent new records dating back two centuries at UC for a single graduating class.

UC will award 539 associate degrees, 4,549 baccalaureate degrees, 252 doctoral degrees, 1,886 master’s degrees, 3 micro-credentials and 292 professional certificates.

This year 15% of graduates are first-generation college students. And 210 students come from Cincinnati Public Schools. Nearly 3% of grads are U.S. veterans or dependents of veterans.

New this year, three students will graduate from UC’s micro-credentialing program as electronic health records specialists. UC also will celebrate its first spring graduating class in the new master’s of legal studies program.

UC has seen a dramatic increase in master’s graduates in information technology and baccalaureate graduates in cybersecurity in the College of Education, Criminal Justice, and Human Services. Meanwhile, the College of Engineering and Applied Science has seen a surge in graduates in its computer science and biomedical engineering programs, reflecting a growing interest in these fields.

The spring class of 2024 has the largest-ever percentage of master’s and doctoral graduates, representing more than 28% of graduates. And nearly 15% of grads participated through distance learning programs.

Graduates hail from 84 of Ohio’s 88 counties, a new record. They come from all 50 states and 81 countries as far away as Australia, New Zealand, South Africa, the Philippines and Japan.

Women represent 56% of the spring class of 2024. And 57 grads will celebrate their birthday during the three days of commencement.

UC College of Design, Architecture, Art, and Planning graduate Tim Brown will receive an honorary degree during UC's spring commencement at Fifth Third Arena. Photo/Lisa Ventre/UC

Spirit of entrepreneurship

The Board of Trustees will award an honorary degree to UC graduate and international entrepreneur Timothy Brown, co-founder and chief innovation officer for the sustainable shoe and clothing company Allbirds.

Brown, a native of Wellington, New Zealand, is a 2005 graduate of UC’s College of Design, Architecture, Art, and Planning, where he majored in graphic design and worked in UC’s top-rated co-op program.

Tim Brown was a standout soccer player at UC. Photo/UC Athletics

At UC, he was a standout soccer player who turned professional, playing for the Richmond Kickers in Virginia, the Newcastle Jets in Australia and the Wellington Phoenix in New Zealand.

He used his experience as a professional athlete and a designer to make what Time magazine called “the world’s most comfortable shoe.” Allbirds uses natural and sustainable fibers like wool.

“I consider my design education such a valuable thing for what I’m now doing as an entrepreneur,” Brown said in a 2016 interview.

Brown returned to campus in 2019 to accept UC Athletics’ Outstanding Alumni Award. While there, he addressed students at his alma mater, telling them not to listen to naysayers about what is and is not possible. He was warned how difficult a task it would be to succeed in Division 1 soccer while taking on a demanding program like graphic design. 

“I had to fight through the warnings and prove people wrong,” he told students. 

UC College of Engineering and Applied Science Professor Neil Armstrong folds a paper airplane with his aerospace engineering students during a lesson on flight characteristics. Armstrong taught at UC after serving as a test pilot and being the first person to set foot on the moon. Photo/UC Marketing + Brand

Following a legend

UC graduate Chin Hua “Odin” Ou is following in the footsteps of Neil Armstrong, the first person to walk on the moon. Armstrong came to UC to teach aerospace engineering after leaving NASA. Before becoming an astronaut, Armstrong was an engineer and test pilot who worked to improve the aerodynamics of aircraft.

UC College of Engineering and Applied Science graduate Odin Ou wants to design aircraft. Photo/Provided

Like Armstrong, Ou wants to help design better airplanes. He will accept a master’s degree in aerospace engineering from UC’s College of Engineering and Applied Science.

Among his UC highlights was publishing a paper on unmanned aerial vehicle design at a conference and competing in an international competition in Fort Worth, Texas, as a member of the UC AeroCats. They finished an impressive fourth overall in the 2023 competition.

Ou said the trip to Texas was epic.

“We built two types of UAV. To transfer them to Texas, we rented a truck and van to drive down from Cincinnati,” he said. “It’s the biggest road trip I’ve taken.” They celebrated their good finish at a barbecue restaurant.

“I would definitely recommend the aerospace engineering program at UC. It’s a great place to study,” he said. “The environment here is very friendly. And there are a lot of resources to use.”

Ou is an international student from Taiwan. During his time at UC, he traveled to Montana, Washington and Florida. And he went to Detroit to visit his younger brother who is studying transportation design there.

Their father is a retired electrical engineer. He is excited to see his parents at commencement. Afterward, he will return to Taiwan to complete his mandatory military service. And then he hopes to work for an aviation company.

“After all these years of studying, it’s a big end to me — and a new chapter,” he said.

UC graduates Jaina and Benton Hellmann, pictured with their family, will graduate together this spring. Photo/Provided

No sibling rivalry

Siblings Jaina and Benton Hellmann are graduating together this year.

Jaina is an Honors Program student who conducted research at a pediatric hospital while studying chemistry in UC’s College of Arts and Sciences.

“Our project focuses on how your body develops an immune ‘memory’ against antigens that have invaded you before,” she said. “I never dreamed of doing biomedical research. I’ve seen myself grow as a researcher and team member at UC.”

Siblings Jaina and Benton Hellmann are graduating together this spring. Photo/Provided

Now she plans to pursue a doctorate in environmental engineering in UC’s College of Engineering and Applied Science.

“She’s the brains of the family,” her brother, Benton, joked.

Benton has a job offer in cybersecurity after graduating with a bachelor’s degree from the School of Information Technology in UC’s College of Education, Criminal Justice, and Human Services.

“I took some computer classes in high school and that kicked things off with me. I wanted to have a secure future so information technology was a safe bet,” he said.

Benton said he especially liked living on campus.

“It was easy to get to a game and be a part of campus life. And it was convenient to get help from classmates,” he said. 

Jaina said she tried to balance academics with research and her social life. She took part in RallyCats, a student spirit organization that provides a cheering section for a range of student sports. Their motto: They play the games; we make the noise!

“There are so many fun memories, like when we beat Houston to make the College Football Playoff and stormed the field. Being a part of that is something I’ll never forget,” she said.

She wants to pursue a career in water-quality monitoring.

“UC has been a really good place for me to discover who I am as a person in and out of the classroom,” she said.

UC will celebrate spring commencement over three days at Fifth Third Arena. Photo/Andrew Higley/UC Marketing + Brand

Pushing frontiers of medicine

Darl Jacob is earning a bachelor’s degree in chemistry from UC’s College of Arts and Sciences, where he conducted research in immunology.

“We were working on therapeutic interventions for people who are diagnosed with immune deficiencies,” he said.

He has been interested in chemistry since high school. The field of immunology is seeing dramatic advancements in treatments of diseases like cancer, he said.

“It’s been interesting to see how you can modify the body’s immune cells,” he said.

Jacob was born in India but grew up in the United Arab Emirates. His family will come from two continents to attend his commencement. Meanwhile, his brother is in Europe, working on a graduate internship in electrical engineering in the United Kingdom.

“My mom and dad are coming from the UAE and my grandmother is coming from India,” he said.

His dad also works in chemistry as a biochemist.

“The good thing is my dad was able to give me a lot of insights about opportunities in chemistry, particularly if I wanted to go into research,” he said.

After graduation, Jacob will attend Brown University for graduate school.

“One of the biggest lessons I learned is that resilience is a good thing. And it’s really important to ask questions when you don’t know something,” he said. “That’s something I’ll take to grad school.”

Featured image at top: UC students will celebrate commencement over three days at Fifth Third Arena. Photo/Andrew Higley/UC Marketing + Brand

Become a Bearcat

Whether you’re a first-generation student or from a family of Bearcats, UC is proud to support you at every step along your journey. We want to make sure you succeed — and feel right at home.

• College of Pharmacy
• College of Medicine
• College of Allied Health Sciences
• Student Experience
• Academic Excellence
• Veteran's Affairs
• Alumni Association
• College of Design, Architecture, Art, and Planning
• International
• Lindner College of Business
• College-Conservatory of Music
• Experience-based Learning
• College of Arts and Sciences
• College of Cooperative Education and Professional Studies
• College of Education, Criminal Justice, & Human Services
• Blue Ash College
• Clermont College
• Graduate School
• College of Law
• College of Nursing
• Next Lives Here
• College of Engineering and Applied Science

Related Stories

April 22, 2024

UC will confer degrees to 7,521 degrees to 7,391 students. (Some students are earning multiple degrees.) Both represent new records at UC for a single graduating class dating back two centuries.

2023: A year in review

December 15, 2023

Review the University of Cincinnati's historic and productive year in 2023 through our year-in-review website.

Path to 50K: A journey defined by our impact

August 28, 2023

University of Cincinnati President Neville G. Pinto shares the importance of UC's impact as enrollment projected to eclipse 50,000 students for first time in university history.

Trains Moscow to Elektrostal: Times, Prices and Tickets

• Train Times
• Seasonality
• Accommodations

Moscow to Elektrostal by train

The journey from Moscow to Elektrostal by train is 32.44 mi and takes 2 hr 7 min. There are 71 connections per day, with the first departure at 12:15 AM and the last at 11:46 PM. It is possible to travel from Moscow to Elektrostal by train for as little as or as much as . The best price for this journey is .

Get from Moscow to Elektrostal with Virail

Virail's search tool will provide you with the options you need when you want to go from Moscow to Elektrostal. All you need to do is enter the dates of your planned journey, and let us take care of everything else. Our engine does the hard work, searching through thousands of routes offered by our trusted travel partners to show you options for traveling by train, bus, plane, or carpool. You can filter the results to suit your needs. There are a number of filtering options, including price, one-way or round trip, departure or arrival time, duration of journey, or number of connections. Soon you'll find the best choice for your journey. When you're ready, Virail will transfer you to the provider's website to complete the booking. No matter where you're going, get there with Virail.

How can I find the cheapest train tickets to get from Moscow to Elektrostal?

Prices will vary when you travel from Moscow to Elektrostal. On average, though, you'll pay about for a train ticket. You can find train tickets for prices as low as , but it may require some flexibility with your travel plans. If you're looking for a low price, you may need to prepare to spend more time in transit. You can also often find cheaper train tickets at particular times of day, or on certain days of the week. Of course, ticket prices often change during the year, too; expect to pay more in peak season. For the lowest prices, it's usually best to make your reservation in advance. Be careful, though, as many providers do not offer refunds or exchanges on their cheapest train tickets. Unfortunately, no price was found for your trip from Moscow to Elektrostal. Selecting a new departure or arrival city, without dramatically changing your itinerary could help you find price results. Prices will vary when you travel from Moscow to Elektrostal. On average, though, you'll pay about for a train ticket. If you're looking for a low price, you may need to prepare to spend more time in transit. You can also often find cheaper train tickets at particular times of day, or on certain days of the week. Of course, ticket prices often change during the year, too; expect to pay more in peak season. For the lowest prices, it's usually best to make your reservation in advance. Be careful, though, as many providers do not offer refunds or exchanges on their cheapest train tickets.

How long does it take to get from Moscow to Elektrostal by train?

The journey between Moscow and Elektrostal by train is approximately 32.44 mi. It will take you more or less 2 hr 7 min to complete this journey. This average figure does not take into account any delays that might arise on your route in exceptional circumstances. If you are planning to make a connection or operating on a tight schedule, give yourself plenty of time. The distance between Moscow and Elektrostal is around 32.44 mi. Depending on the exact route and provider you travel with, your journey time can vary. On average, this journey will take approximately 2 hr 7 min. However, the fastest routes between Moscow and Elektrostal take 1 hr 3 min. If a fast journey is a priority for you when traveling, look out for express services that may get you there faster. Some flexibility may be necessary when booking. Often, these services only leave at particular times of day - or even on certain days of the week. You may also find a faster journey by taking an indirect route and connecting in another station along the way.

How many journeys from Moscow to Elektrostal are there every day?

On average, there are 71 daily departures from Moscow to Elektrostal. However, there may be more or less on different days. Providers' timetables can change on certain days of the week or public holidays, and many also vary at particular times of year. Some providers change their schedules during the summer season, for example. At very busy times, there may be up to departures each day. The providers that travel along this route include , and each operates according to their own specific schedules. As a traveler, you may prefer a direct journey, or you may not mind making changes and connections. If you have heavy suitcases, a direct journey could be best; otherwise, you might be able to save money and enjoy more flexibility by making a change along the way. Every day, there are an average of 18 departures from Moscow which travel directly to Elektrostal. There are 53 journeys with one change or more. Unfortunately, no connection was found for your trip from Moscow to Elektrostal. Selecting a new departure or arrival city, without dramatically changing your itinerary could help you find connections.

Book in advance and save

If you're looking for the best deal for your trip from Moscow to Elektrostal, booking train tickets in advance is a great way to save money, but keep in mind that advance tickets are usually not available until 3 months before your travel date.

Stay flexible with your travel time and explore off-peak journeys

Planning your trips around off-peak travel times not only means that you'll be able to avoid the crowds, but can also end up saving you money. Being flexible with your schedule and considering alternative routes or times will significantly impact the amount of money you spend on getting from Moscow to Elektrostal.

Always check special offers

Checking on the latest deals can help save a lot of money, making it worth taking the time to browse and compare prices. So make sure you get the best deal on your ticket and take advantage of special fares for children, youth and seniors as well as discounts for groups.

Unlock the potential of slower trains or connecting trains

If you're planning a trip with some flexible time, why not opt for the scenic route? Taking slower trains or connecting trains that make more stops may save you money on your ticket – definitely worth considering if it fits in your schedule.

Best time to book cheap train tickets from Moscow to Elektrostal

The cheapest Moscow - Elektrostal train tickets can be found for as low as $35.01 if you’re lucky, or $54.00 on average. The most expensive ticket can cost as much as $77.49.

Find the best day to travel to Elektrostal by train

When travelling to Elektrostal by train, if you want to avoid crowds you can check how frequently our customers are travelling in the next 30-days using the graph below. On average, the peak hours to travel are between 6:30am and 9am in the morning, or between 4pm and 7pm in the evening. Please keep this in mind when travelling to your point of departure as you may need some extra time to arrive, particularly in big cities!

Moscow to Elektrostal CO2 Emissions by Train

Anything we can improve?

Frequently Asked Questions

Go local from moscow, trending routes, weekend getaways from moscow, international routes from moscow and nearby areas, other destinations from moscow, other popular routes.

CASE REPORT article

Case report: from negative to positive: a remarkable journey of er, pr and her2 status in a patient with metastatic breast cancer.

• 1 Department of Oncology, Jiujiang University Affiliated Hospital, Jiujiang, Jiangxi, China
• 2 Department of Ultrasonic Diagnosis, Jiujiang University Affiliated Hospital, Jiujiang, Jiangxi, China

Breast cancer is the most common malignant tumor in women, posing a serious threat to women’s health. HER2 has been identified as a key oncogene and prognostic factor in breast cancer. Recent studies have reported inconsistencies in ER, PR, and/or HER2 expression between primary breast tumors and metastatic lesions. Rarely is it reported that all three biomarkers experience conversion. In this report, we present the case of a female patient with relapsed and metastatic breast cancer, whose histology transformed from initially triple-negative to Luminal-B type (HER2 positive) (i.e., ER, PR, and HER2 positive). She underwent systematic chemotherapy, targeted therapy, and cranial radiotherapy, which was followed by maintenance treatment with targeted and endocrine therapy. Currently, she has been in nearly complete remission (nCR) for more than 12 months. For recurrent and metastatic breast cancer, it is necessary to perform the second biopsy for metastases, which would contribute to precision treatment and prognosis improvement.

Introduction

According to the latest National Cancer Report, breast cancer is the most common malignant tumor and the second leading cause of cancer mortality in Chinese females ( 1 ). The therapeutic strategies for newly-diagnosed breast cancer include surgery, chemotherapy, radiotherapy, targeted therapy, and endocrine therapy. The choice of treatment depends on the stage of TNM, pathology, molecular types, and physical conditions ( 2 ). For relapsed and metastatic breast cancer, the treatment strategy is primarily based on the original pathological and molecular types of the cancer ( 2 ). Recently, several retrospective studies have reported inconsistent biomarkers, i.e. estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2), between the primary lesions and metastases of breast cancer ( 3 – 6 ). The majority of the discordance occurred only one or two of ER, PR and HER2 status. It is rarely reported that all three biomarkers simultaneously changed between primary lesion and recurrent & metastases. In this report, we present a case of a female patient with stage IIIA breast cancer who experienced a transition from initial triple-negative to Luminal-B type (HER2 positive) after recurrence and metastasis. As a result, she received anti-HER2 therapy plus chemotherapy and achieved nearly complete remission (nCR).

Case report

On March 2, 2018, a 31-year-old woman complained of a palpable mass in the left breast for more than 2 months. The serum levels of CEA and CA153 were 22.5ng/ml and 46.8U/ml, respectively. Then she was diagnosed with left breast cancer and underwent a modified radical resection at Jiujiang University Affiliated Hospital. Postoperative pathology revealed invasive ductal carcinoma of the left breast, non-specific type, with left axillary lymph nodes metastasis (5/23). Immunohistochemical examinations showed ER (-), PR (-), HER2 (-), and Ki-67 (80% +), indicating triple-negative type breast cancer ( Figure 1 ). Because the patient possessed a certain degree of medical knowledge, she required further examination of HER2 by fluorescence in situ hybridization (FISH). The negative status of HER2 was typically confirmed by FISH.

Figure 1 The changes of biomarkers between newly-diagnosed and relapsed biopsies. (A–D) Negative expression of ER, PR, and HER-2. (E–H) Positive expression of ER, PR, and HER-2.

The stage of TNM was pT2N2aM0, stage IIIA. Due to the high risk of relapse (≥4 axillary lymph node positive), the patient received adjuvant chemotherapy since April 4, 2018. Specifically, the combined regimen consisted of epriubicin and cyclophosphamide (EC) for 4 cycles with 1 cycle every 3 weeks. Then, she was treated with albumin-bound paclitaxel (T) for 4 cycles per 3 weeks cycle. On Oct. 10, adjuvant radiotherapy was administered to the chest wall and regional lymph node drainage field, with 25 daily doses (fractions) of 2.0 Gy to a total dose of 50Gy over 5 weeks. The patient was followed up regularly and examined every 3 months during the first 2 years after surgery, including tumor markers, breast ultrasound, chest and abdominal CT, and brain MRI examinations. Sine the third year after operation, she received regular evaluation every 6 months. The patient was in good condition and no signs of tumor recurrence were found.

In December 2022, the patient complained of right upper abdominal discomfort, loss of appetite and occasional nausea. The patient was examined at our Hospital on December 22, 2022. The CEA level was 32.86ng/ml. The CA153 level was greater than 342.5ng/ml. Abdominal CT indicated multiple metastatic tumors of the liver ( Figure 2 ). On January 4, 2023, the brain magnetic resonance imaging (MRI) was performed. It found an abnormal signal in the right frontal nodule, suggesting metastasis. Cervical lymph node ultrasonography showed abnormal structural lymph nodes in the bilateral neck region II and left neck region V. The maximum diameter of lymph nodes was only 1.4 cm. Also, the physical examination showed no significantly palpable superficial lymph nodes. Thus, the patient received percutaneous color ultrasound-guided needle biopsy of liver biopsies on January 4, 2023. Pathological findings supported that the liver metastases were consistent with breast cancer. Immunohistochemistry results showed ER (70% +), PR (40% +), Ki-67 (40% +), as well as the positive expression of HER2 (2+). Furthermore, the positive status of HER2 was confirmed by FISH detection ( Figure 1 ). Finally, the patient was diagnosed with Luminal B type (HER2 positive), i.e. ER, PR, and HER2 positive. The patient received stereotactic radiotherapy (SRT) with DT50Gy/10F for the solid brain metastasis on January 8, 2023. Concurrently, the patient received the combined treatment of docetaxel(D), trastuzumab (H), and pertuzumab(P) (D-HP) for 6 cycles, with each cycle lasting 3 weeks, starting from January 11, 2023. The clinical efficacy was evaluated based on the Response Evaluation Criteria for Solid Tumors (RECIST1.1), including complete response (CR) and partial remission (PR). CR indicates that all lesions disappear completely, and all pathological lymph nodes reduce to normal size (short diameter < 1cm), lasting for more than 1 month. PR means that the total maximum diameter of all measurable lesions reduces by over 30%, lasting for more than 1 month. Nearly CR (nCR) refers to that the majority of all measurable lesions disappear, but only a few tiny residual foci remain.

Figure 2 The CT changes of different metastatic lesions from liver (A–D) .

After 3 cycles of treatment, the clinical efficacy showed partial remission (PR). After 6 cycles of treatments, the patient achieved complete remission (CR) of cervical metastatic lymph nodes and brain metastasis ( Figure 3 ). For liver metastases, the clinical efficacy showed partial remission (PR). Since May 21, 2023, the patient began to receive maintenance therapy, which included trastuzumab, leuprorelin, letrozole, and Abemaciclib (an inhibitor of CDK4/6). Currently, the patient is receiving regular maintenance therapy without any clear discomfort. In December 2023, the latest efficacy was evaluated, and the hepatic metastatic lesions almost disappeared, indicating nCR ( Figure 2 ). She has achieved progression-free survival (PFS) of over 12 months and the overall survival of 69 months up to now ( Figure 4 ). The patient still undergoes close follow-up and receives regular examination every 6 months.

Figure 3 Magnetic resonance imaging (MRI) examinations of right frontal lobe metastasis (red arrow). (A, D) The presence of solid brain metastasis (diameter of 1 cm). (B, E) and (C, G) The disappearance of brain metastasis.

Figure 4 Detailed time course of the patient's clinical course and therapeutic regimens.

Previously, it was believed that breast cancer was a static disease in terms of pathology. However, in-depth molecular studies have found that breast cancer should be considered as a spatially and temporally dynamic disease, i.e. that the heterogeneities exist in different sites between primary tumors and metastases, and different phases between initial diagnosis and recurrence ( 7 ). The phenomenon of heterogeneity between primary and metastatic lesions has attracted increasing attention from clinicians in the field of breast cancer. Timmer M et al. compared the status of ER, PR, and HER2 in primary tumors with brain metastases in 24 patients with breast cancer. They found that 25-37.5% of patients exhibited discordant receptor status between the primary tumor and brain lesions ( 4 ). Nishimura R et al. reported the changes in ER, PR, Ki-67, and HER2 status between primary and recurrent lesions in 97 patients with breast cancer. Following relapse, ER and PR decreased while Ki-67 increased. Subtype changes occurred in 24.7% of the patients ( 5 ). Lin M et al. compared the changes in HER2 status between primary tumors and paired recurrent/metastatic lesions in 1299 patients with breast cancer. The incidence of discordance was 28.5% (370/1299), indicating the conversion of primary-to-metastatic HER2 status ( 3 ). The results indicated that the heterogeneity between primary and metastatic lesions is an important clinical issue that cannot be ignored.

The underlying mechanisms have been partly ascribed to clonal evolutions, which contribute to genetic heterogeneity during malignant progression. Sprouffske K et al. faithfully mimicked the clonal evolution of metastasis process in the patient-derived tumor xenografts (PDX) from breast cancer. During the process of clonal selection, some subclones remain stable, some expand, and others vanish over time. Furthermore, clonal evolution leads to genetic heterogeneity and different clinical outcomes ( 8 ). A prospective analysis of circulating tumor DNA (ctDNA) was performed by next-generation sequencing (NGS) in 37 patients with HR-positive, HER2-negative breast cancer who were classified as secondary resistance. The occurrences of new mutations were 0% (0/9) for the chemotherapy group, 42.1% (8/19) for the CDK4/6 inhibitors plus endocrine treatment (CE group), and 36.3% (4/11) for the chemotherapy followed by CE group (p=0.024). The results strongly indicated that chemotherapy or CDK4/6 inhibitors may influence the change of clonal evolution among breast cancer patients ( 9 ). Liquid biopsy by Kujala J et al. detected 56.2 ± 7.2% of somatic variants present both in the matched primary tumor and metastatic sites from breast cancer patients. Apparently, liquid biopsy may identify novel driver variants and therapeutic targets absent from the tumor tissue DNA ( 10 ). In the clinical setting, ctDNA may be an ideal surrogate for longitudinal monitoring of genetic heterogeneity from breast cancer patients who can’t obtain tissue specimen ( 7 ). Another potential explanation may be attributed to that a second local lesion ( in situ or invasive) could have developed concomitantly with the primary DCIS or in the period between the primary tumor and recurrence, which could be a plausible explanation for the luminal metastases. Thus, it is necessary and important to follow-up the patients with breast cancer.

According to the studies, all the insistences occurred in only one or two of three receptors (ER, PR, and HER2 receptors) in breast cancer patients at the stages of initial diagnosis and recurrence & metastasis ( 3 – 5 ). However, the transition from triple-negative to ER, PR, and HER2 positive status was rarely observed. In our report, we present a case of a female patient newly diagnosed with triple-negative breast cancer, who experienced multiple metastases to the liver, brain, and cervical lymph nodes 57 months after the operation. A re-biopsy of the liver metastases revealed a conversion into ER, PR, and HER2 positive status. In this case, the liver was the optimal site available for re-biopsy. As a result, the patient received accurate detection and precision medicine. Encouragingly, the patient achieved nCR for all the metastases after systematic treatments. This re-confirmed the correct diagnosis after disease relapse and metastasis. In contrast, re-biopsy from brain metastasis is not easily available for breast cancer patients. In this clinical setting, liquid biopsy of ctDNA [including cerebrospinal fluid (CSF)] may be an alternative option for these types of patients ( 11 ).

Conclusions

The discrepancy in the biomarkers of ER, PR, and HER2 status presents a significant clinical challenge in patients with breast cancer, particularly between primary tumors and metastatic lesions. Simultaneous conversion of all three biomarkers is a rare occurrence during the disease progression of breast cancer. This study presents a case of a female patient with initial triple-negative breast cancer who transformed to ER, PR, and HER2-positive status after recurrence and metastasis. Consequently, she underwent systematic treatment, including chemotherapy, targeted therapy, cranial radiotherapy, and maintenance treatment. The patient achieved a promising complete response (nCR) for over 12 months up to now. The final results of CLEOPATRA study reported that mOS and 8-year OS rates were significantly higher in the D-HP group than that in was D-H (docetaxel-trastuzumab) group ( mOS : 57.1 vs . 40.8 months; 8-year OS rates : 37% vs . 23%) ( 12 ). Therefore, we have reasons to believe that the patient is likely to have an excellent outcome. This report highlights the necessity and importance of secondary biopsy in patients with breast cancer, which could significantly facilitate precise diagnosis and treatment.

Data availability statement

The original contributions presented in the study are included in the article/supplementary material. Further inquiries can be directed to the corresponding authors.

Ethics statement

The studies involving humans were approved by Ethic Committee of Jiujiang University Affiliated Hospital. The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study. Written informed consent was obtained from the individual(s) for the publication of any potentially identifiable images or data included in this article.

Author contributions

JH: Investigation, Methodology, Writing – original draft. LL: Data curation, Formal analysis, Methodology, Writing – original draft. JD: Conceptualization, Software, Writing – review & editing.

The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

1. Tao X, Li T, Gandomkar Z, Brennan PC, Reed WM. Incidence, mortality, survival, and disease burden of breast cancer in China compared to other developed countries. Asia Pac J Clin Oncol . (2023) 19:645–54. doi: 10.1111/ajco.13958

PubMed Abstract | CrossRef Full Text | Google Scholar

2. Loibl S, Poortmans P, Morrow M, Denkert C, Curigliano G. Breast cancer. Lancet . (2021) 397:1750–69. doi: 10.1016/S0140-6736(20)32381-3

3. Lin M, Luo T, Jin Y, Zhong X, Zheng D, Zeng C, et al. Her2-low heterogeneity between primary and paired recurrent/metastatic breast cancer: implications in treatment and prognosis. Cancer . (2023) 130:851–62. doi: 10.1002/cncr.35101

4. Timmer M, Werner JM, Rohn G, Ortmann M, Blau T, Cramer C, et al. Discordance and conversion rates of progesterone-, estrogen-, and her2/neu-receptor status in primary breast cancer and brain metastasis mainly triggered by hormone therapy. Anticancer Res . (2017) 37:4859–65. doi: 10.21873/anticanres.11894

5. Nishimura R, Osako T, Okumura Y, Tashima R, Toyozumi Y, Arima N. Changes in the er, pgr, her2, p53 and ki-67 biological markers between primary and recurrent breast cancer: discordance rates and prognosis. World J Surg Oncol . (2011) 9:131. doi: 10.1186/1477-7819-9-131

6. Pellas U, Bauer A, Baros IV, Fattorini C, Tot T. Her2-low metastases of her2-negative primary tumors: a single institution analysis of intertumoral and internodal heterogeneity in node-positive breast cancer. Front Oncol . (2023) 13:1167567. doi: 10.3389/fonc.2023.1167567

7. Kavan S, Kruse TA, Vogsen M, Hildebrandt MG, Thomassen M. Heterogeneity and tumor evolution reflected in liquid biopsy in metastatic breast cancer patients: a review. Cancer Metastasis Rev . (2022) 41:433–46. doi: 10.1007/s10555-022-10023-9

8. Sprouffske K, Kerr G, Li C, Prahallad A, Rebmann R, Waehle V, et al. Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models. Comput Struct Biotechnol J . (2020) 18:323–31. doi: 10.1016/j.csbj.2020.01.008

9. Decker T, Bichler M, Birtel A, Fischer G, Geiger K, Gaenger S, et al. Clonal evolution in patients with hormone receptor positive, her-2 negative breast cancer treated with chemotherapy or cdk4/6 inhibitors. Oncol Res Treat . (2022) 45:248–53. doi: 10.1159/000523758

10. Kujala J, Hartikainen JM, Tengstrom M, Sironen R, Auvinen P, Kosma VM, et al. Circulating cell-free dna reflects the clonal evolution of breast cancer tumors. Cancers (Basel) . (2022) 14:1332. doi: 10.3390/cancers14051332

11. Fitzpatrick A, Iravani M, Mills A, Vicente D, Alaguthurai T, Roxanis I, et al. Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype. Nat Commun . (2023) 14:7408. doi: 10.1038/s41467-023-43242-x

12. Swain S, Miles D, Kim S, Im Y, Im S, Semiglazov V, et al. Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study. Lancet Oncol . (2020) 21:519–30. doi: 10.1016/S1470-2045(19)30863-0

Keywords: breast cancer, ER, PR, HER2, transformation, negative, positive

Citation: Huang J, Liu L and Ding J (2024) Case report: From negative to positive: a remarkable journey of ER, PR and HER2 status in a patient with metastatic breast cancer. Front. Oncol. 14:1381541. doi: 10.3389/fonc.2024.1381541

Received: 03 February 2024; Accepted: 15 April 2024; Published: 26 April 2024.

Reviewed by:

Copyright © 2024 Huang, Liu and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Jianghua Ding, [email protected]

† These authors have contributed equally to this work

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.